SCHEMBL6157040

SCHEMBL6157040

O=S(=O)(O)c1cc(O)c2c(O)cc(S(=O)(=O)O)cc2c1.O=[N+]([O-])c1c(O)c(O)c2ccccc2c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.47
CYP2C9 P11712 2/20 0.44
CYP1A2 P05177 2/20 0.44
MAPK1 P28482 1/20 0.44
DNASE1L3 Q13609 1/20 0.44
NT5E P21589 2/20 0.43
APEX1 P27695 1/20 0.43
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CASP6 P55212 4/20 0.42
NSD2 O96028 3/20 0.42
GAA P10253 1/20 0.42
PLCG1 P19174 1/20 0.42
DNMT1 P26358 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTPN1 P18031 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890966 0.78 S100A4 (0.74) S100A4ALDH1A1TDP1CASP6GAA
SCHEMBL3191789 0.75 S100A4 (0.61) S100A4ALDH1A1HPGDTDP1CASP6
SCHEMBL66310 0.72 NT5E (0.74) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
SCHEMBL11502500 0.72 NT5E (0.74) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
SCHEMBL564558 0.72 NT5E (0.74) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
SCHEMBL29429654 0.72 NT5E (0.74) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
SCHEMBL9805944 0.71 NT5E (0.71) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
Sulfuric Acid SCHEMBL9775004 0.71 NT5E (0.71) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
SCHEMBL564556 0.71 NT5E (0.71) CYP2C9CYP1A2MAPK1DNASE1L3NT5E
Water SCHEMBL11045842 0.71 NT5E (0.71) CYP2C9CYP1A2MAPK1DNASE1L3NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1504257-A1 DIAGNOSTIC TEST FOR ELEMENTAL IMBALANCES Future Data Inc. (US) 2005-02-09 EP claimed
WO-2003091725-A1 DIAGNOSTIC TEST FOR ELEMENTAL IMBALANCES FUTURE DATA INC. (US) 2003-11-06 WO claimed