Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.74 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621885 | 0.89 | S100A4 (0.83) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29849465 | 0.89 | S100A4 (0.83) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7915412 | 0.87 | S100A4 (0.80) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25322776 | 0.82 | S100A4 (0.67) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17233508 | 0.82 | CASP6 (0.54) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2829878 | 0.82 | S100A4 (0.64) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29674860 | 0.79 | CYP3A4 (0.70) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2285808 | 0.79 | CYP3A4 (0.70) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3191789 | 0.78 | S100A4 (0.61) | S100A4CASP6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6157040 | 0.78 | S100A4 (0.47) | S100A4CASP6CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821786-B2 | HOME/SELF-DIAGNOSIS; MICROTRACINGS | FUTURE DATA INC. | 2004-11-23 | — | — | US | claimed |
| US-20030203495-A1 | Diagnostic test for elemental imbalances | FUTURE DATA INC. | 2003-10-30 | — | — | US | claimed |
| US-6821786-B2 | HOME/SELF-DIAGNOSIS; MICROTRACINGS | FUTURE DATA INC. | 2004-11-23 | — | — | US | disclosed |