Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 13/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878832 | 1.00 | VDR (0.52) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6878835 | 0.82 | NR4A2 (0.44) | MAOBMAOANR4A1NR4A2NR4A3 | |
| SCHEMBL6158301 | 0.77 | NPC1 (0.42) | MAOBMAOANR4A1NR4A2NR4A3 | |
| SCHEMBL6881407 | 0.77 | NPC1 (0.42) | MAOBMAOANR4A1NR4A2NR4A3 | |
| SCHEMBL2107507 | 0.74 | VDR (0.66) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL2107505 | 0.74 | VDR (0.66) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6155486 | 0.74 | VDR (0.52) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6155478 | 0.74 | VDR (0.52) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6155494 | 0.74 | VDR (0.52) | VDRMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6879640 | 0.74 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |