Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158301 | 1.00 | NPC1 (0.42) | NPC1RAB9ALMNAMAPK1HTT | |
| SCHEMBL6879640 | 0.78 | KDM4E (0.44) | NPC1RAB9ALMNAMAPK1HTT | |
| SCHEMBL6155720 | 0.78 | KDM4E (0.44) | NPC1RAB9ALMNAMAPK1HTT | |
| SCHEMBL6878835 | 0.78 | NR4A2 (0.44) | NPC1RAB9AL3MBTL1PPARGPPARA | |
| SCHEMBL6155669 | 0.78 | NPC1 (0.51) | NPC1RAB9AHIF1AALDH1A1GAA | |
| SCHEMBL6155665 | 0.78 | NPC1 (0.51) | NPC1RAB9AHIF1AALDH1A1GAA | |
| SCHEMBL6878832 | 0.77 | VDR (0.52) | HIF1AMAOBMAOANR4A1NR4A2 | |
| SCHEMBL6157088 | 0.77 | VDR (0.52) | HIF1AMAOBMAOANR4A1NR4A2 | |
| SCHEMBL7639971 | 0.71 | MAOB (0.43) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL30442255 | 0.71 | MAOB (0.62) | NPC1RAB9AALDH1A1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |