Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156550 | 0.97 | BCL2 (0.41) | MTNR1AMTNR1BBCL2PPARGPPARD | |
| SCHEMBL6156203 | 0.91 | MTNR1A (0.42) | MTNR1AMTNR1BBCL2PPARGPPARD | |
| SCHEMBL6156500 | 0.88 | MTNR1A (0.42) | MTNR1AMTNR1BBCL2PPARGPPARD | |
| SCHEMBL6156102 | 0.87 | VDR (0.48) | MTNR1AMTNR1BAPP | |
| SCHEMBL6155372 | 0.84 | BCL2 (0.40) | BCL2CFD | |
| SCHEMBL6155129 | 0.84 | VDR (0.48) | MTNR1AMTNR1BBCL2APP | |
| SCHEMBL6157286 | 0.82 | BCL2 (0.41) | MTNR1AMTNR1BBCL2PPARALTB4R | |
| SCHEMBL6156106 | 0.82 | APP (0.42) | MTNR1AMTNR1BBCL2APP | |
| SCHEMBL6157274 | 0.80 | BCHE (0.47) | — | |
| SCHEMBL6156554 | 0.79 | BCL2 (0.43) | MTNR1AMTNR1BBCL2PPARALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |