SCHEMBL6157399

SCHEMBL6157399

N=C(N)NCc1ccc(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)[C@@H]2CC(=O)O)cc1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.81
ITGA2B P08514 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7284992 0.99 ITGB3 (0.79) ITGB3ITGA2B
SCHEMBL6159953 0.89 ITGB3 (1.00) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7296379 0.89 ITGB3 (0.73) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7022993 0.89 ITGB3 (0.98) ITGB3ITGA2B
SCHEMBL6156375 0.88 ITGB3 (0.82) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7287107 0.87 ITGB3 (0.81) ITGB3ITGA2B
SCHEMBL7285056 0.86 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL8900162 0.85 ITGB3 (0.81) ITGB3ITGA2B
SCHEMBL6156687 0.85 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL6156386 0.84 ITGB3 (0.59) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050187249-A1 An aqueous solution of a physiologically active substance which may have a substituent and which has an amidino group, the solution having a pH > 2 and -/< than 4; storage stability; parental injections; 2-[4-[((3S)-1-acetoimidoyl-3-pyrrolidinyl)oxy]phenyl] -3-(7-amidino-2-naphthyl)propionic acid; kits DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-08-25 US disclosed
EP-1504755-A1 LYOPHILIZATION PRODUCT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-02-09 EP disclosed
US-5888531-A ACTIVE MATERIAL STABILIZED WITH DISACCHARIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-03-30 US disclosed
EP-0750913-A2 Disaccharide containing freeze-dried preparation for pharmaceutical use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050187249-A1 An aqueous solution of a physiologically active substance which may have a substituent and which has an amidino group, the solution having a pH > 2 and -/< than 4; storage stability; parental injections; 2-[4-[((3S)-1-acetoimidoyl-3-pyrrolidinyl)oxy]phenyl] -3-(7-amidino-2-naphthyl)propionic acid; kits NGLY1, IDE, NPPA ITGB3 3735/4885ITGA2B 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.