Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415916 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL12344738 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7419454 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL6159705 | 0.72 | CYP1A2 (0.52) | ALDH1A1MAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL3595617 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL30149949 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7646253 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL30732411 | 0.70 | PSMB8 (0.69) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL9636277 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7905772 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497264-A2 | PREPARATION OF 24-ALKYL ANALOGS OF CHOLECALCIFEROL AND NON-RACEMIC COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087048-A2 | PREPARATION OF 24 ALKYL ANALOGS OF CHOLECALCIFEROL AND NON-RACEMIC COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 2003-10-23 | — | — | WO | disclosed |