Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595617 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL30149949 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL12344745 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL18797576 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL18821334 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL29023732 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL9636277 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL7905772 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL7646253 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL10047096 | 0.79 | PSMB8 (0.64) | ALDH1A1MAPTHTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470763-B2 | Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2013-06-25 | — | — | US | disclosed |
| US-8470763-B2 | Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2013-06-25 | — | — | US | disclosed |
| EP-2233467-B1 | ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2012-09-19 | — | — | EP | disclosed |
| US-20110021624-A1 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2011-01-27 | — | — | US | disclosed |
| US-20110021624-A1 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2011-01-27 | — | — | US | disclosed |
| EP-2233467-A1 | ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021624-A1 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof | AADAT, ASNS, AANAT | ALDH1A1 612/4885MAPT 1742/4885HTT 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.