SCHEMBL615756

SCHEMBL615756

CCCCCCCCC=CCCCCCCCCOP(=O)(OCCCCCCCCC=CCCCCCCCC)OCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 10/20 0.68
LPAR2 Q9HBW0 8/20 0.68
LPAR1 Q92633 5/20 0.68
CYP3A4 P08684 1/20 0.61
FAAH O00519 2/20 0.52
TRPV1 Q8NER1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21439794 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL28522407 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL304774 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL21439796 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL6119544 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL7800702 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL4981336 1.00 LPAR3 (0.68) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL8736972 0.94 LPAR3 (0.62) LPAR3LPAR2LPAR1CYP3A4FAAH
Ammonia Solution, Strong SCHEMBL29013109 0.93 LPAR3 (0.62) LPAR3LPAR2LPAR1CYP3A4FAAH
SCHEMBL11360949 0.91 LPAR3 (0.63) LPAR3LPAR2LPAR1CYP3A4TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID NIPPON SHOKUBAI CO., LTD. (JP) 2024-01-11 US disclosed
US-20230390165-A1 POWDERY SOLID COSMETIC SHISEIDO COMPANY, LTD. (JP) 2023-12-07 US disclosed
US-11696886-B2 Cosmetic SHISEIDO COMPANY, LTD. (JP) 2023-07-11 US disclosed
US-11529293-B2 Oil-in-water emulsion cosmetic SHISEIDO COMPANY, LTD. (JP) 2022-12-20 US disclosed
CN-114514013-A Cosmetic preparation 株式会社资生堂 2022-05-17 CN disclosed
US-20220001443-A1 POWDER DISPERSION COMPOSITION AND DISPERSING METHOD THEREOF SHISEIDO COMPANY, LTD. (JP) 2022-01-06 US disclosed
US-20220000758-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2022-01-06 US disclosed
EP-3881899-A1 COSMETIC Shiseido Company, Ltd. (JP) 2021-09-22 EP disclosed
EP-3881820-A1 POWDER DISPERSION COMPOSITION AND DISPERSING METHOD THEREOF Shiseido Company, Ltd. (JP) 2021-09-22 EP disclosed
US-20210128445-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2021-05-06 US disclosed
EP-1153595-A2 Clear aqueous ceramide composition Takasago International Corporation (JP) 2001-11-14 EP disclosed
EP-1036553-A2 Solid water-in-oil type emulsion cosmetic composition SHISEIDO COMPANY LIMITED (JP) 2000-09-20 EP disclosed
EP-0972508-A1 EXTRACELLULAR MATRIX PRODUCTION PROMOTER SHISEIDO COMPANY LIMITED (JP) 2000-01-19 EP disclosed
EP-0900561-A1 COMPOSITIONS PROMOTING COLLAGEN PRODUCTION SHISEIDO COMPANY LIMITED (JP) 1999-03-10 EP disclosed
US-5853705-A Anti-aging cosmetic composition SHISEIDO COMPANY, LTD. (JP) 1998-12-29 US disclosed
EP-0852949-A2 Use of alpha-amino-acids for enhancing desmosomal degradation or stratum corneum desquamation SHISEIDO COMPANY LIMITED (JP) 1998-07-15 EP disclosed
EP-0815838-A2 External skin treatment composition SHISEIDO COMPANY, LTD. (JP) 1998-01-07 EP disclosed
EP-0797984-A2 Anti-aging cosmetic composition SHISEIDO COMPANY LIMITED (JP) 1997-10-01 EP disclosed
EP-0487404-B1 External dermatological composition HAYASHIBARA BIOCHEM LAB (JP) 1995-10-11 EP disclosed
EP-0487404-A1 External dermatological composition KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1992-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220000758-A1 COSMETIC CUTA, SQLE, FDFT1 LPAR3 1430/4885LPAR2 2204/4885LPAR1 1491/4885
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID PLIN5, PHOSPHO1, PLIN3 LPAR3 33/4885LPAR2 32/4885LPAR1 24/4885
US-11529293-B2 Oil-in-water emulsion cosmetic CUTA, TYR, LPO LPAR3 1012/4885LPAR2 2309/4885LPAR1 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.