Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937598 | 1.00 | CES2 (0.50) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL4937595 | 1.00 | CES2 (0.50) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL6938875 | 0.85 | NR4A1 (0.59) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL28428071 | 0.85 | NR4A1 (0.59) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL11715598 | 0.85 | CES2 (0.48) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL11822730 | 0.85 | ALDH1A1 (0.53) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL11822738 | 0.85 | ALDH1A1 (0.53) | CES2CES1ALOX15TSHRPTGS1 | |
| Bromide SCHEMBL11813077 | 0.83 | ALDH1A1 (0.51) | CES2CES1ALOX15TSHRPTGS1 | |
| Bromide SCHEMBL11813070 | 0.83 | ALDH1A1 (0.51) | CES2CES1ALOX15TSHRPTGS1 | |
| SCHEMBL9510583 | 0.83 | LMNA (0.47) | CES2CES1ALOX15TSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |