Ethylene Glycol

Ethylene Glycol

SCHEMBL6157869

CC(=O)CN(CC(C)=O)CC(C)=O.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.31
EYA2 O00167 1/20 0.30
APP P05067 1/20 0.30
ACE P12821 1/20 0.30
LMNA P02545 1/20 0.30
SLC15A2 Q16348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20067033 0.90 TRPA1 (0.44) TRPA1ALDH1A1TDP1KDM4EALOX15
SCHEMBL416818 0.90 TRPA1 (0.50) TRPA1ALDH1A1TDP1KDM4EALOX15
Hydrochloric Acid SCHEMBL4948054 0.87 TRPA1 (0.47) TRPA1ALDH1A1TDP1KDM4EALOX15
Water SCHEMBL10942489 0.87 TRPA1 (0.47) TRPA1ALDH1A1TDP1KDM4EALOX15
SCHEMBL12779671 0.82 ALOX15 (0.50) TRPA1ALDH1A1TDP1KDM4EMAPT
Sulfuric Acid SCHEMBL11850568 0.79 TRPA1 (0.40) TRPA1ALDH1A1TDP1SMN1; SMN2
SCHEMBL16088171 0.79 TDP1 (0.55) TRPA1ALDH1A1TDP1KDM4EALOX15
SCHEMBL8535878 0.79 TDP1 (0.55) TRPA1ALDH1A1TDP1KDM4EALOX15
SCHEMBL12085022 0.79 TRPA1 (0.40) TRPA1ALDH1A1TDP1KDM4EALOX15
SCHEMBL14526678 0.78 TRPA1 (0.44) TRPA1ALDH1A1TDP1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050028956-A1 Method for making tissue product containing carboxylated cellulosic fibers WEYERHAEUSER COMPANY 2005-02-10 US disclosed
US-20050028955-A1 Tissue product containing carboxylated cellulosic fibers WEYERHAEUSER COMPANY 2005-02-10 US disclosed
EP-1505208-A2 Method for making tissue product containing carboxylated cellulosic fibers Weyerhaeuser Company (US) 2005-02-09 EP disclosed
EP-1505207-A2 Tissue product containing carboxylated cellulosic fibers Weyerhaeuser Company (US) 2005-02-09 EP disclosed