Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25684934 | 0.87 | ALOX15 (0.62) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL18053237 | 0.85 | KDM4E (0.39) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL18053151 | 0.85 | KDM4E (0.39) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL10170635 | 0.84 | ALOX15 (0.38) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| Ethylene Glycol SCHEMBL6157869 | 0.82 | TRPA1 (0.42) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL12191702 | 0.82 | TDP1 (0.55) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL22821372 | 0.82 | ALDH1A1 (0.41) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL15172342 | 0.80 | BLM (0.41) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL3639097 | 0.79 | TDP1 (0.53) | ALOX15KDM4EMAPTSMN1; SMN2TRPA1 | |
| SCHEMBL20067033 | 0.79 | TRPA1 (0.44) | ALOX15KDM4ETRPA1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111979777-A | Durable colorless moisture absorption and sweat releasing composite finishing agent and preparation method thereof | 多恩生物科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| WO-2024085197-A1 | CARRIER MATERIAL FOR LOCALLY RELEASING PARTICULATE SUBSTANCE | 国立大学法人 東京大学 | 2024-04-25 | — | — | WO | disclosed |
| CN-117736124-A | Solid form of naphthylamine mitochondrial autophagy inducer, preparation method, pharmaceutical composition and application thereof | 杭州天玑济世生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023214550-A1 | POLYMER MATERIAL HAVING PHASE SEPARATION STRUCTURE OBTAINED BY CONTROLLING NUMBER OF BRANCHES | 国立大学法人 東京大学 | 2023-11-09 | — | — | WO | disclosed |
| WO-2023214551-A1 | POLYMER MATERIAL HAVING PHASE SEPARATION STRUCTURE | 国立大学法人 東京大学 | 2023-11-09 | — | — | WO | disclosed |
| US-20230174605-A1 | IL-2 SEQUENCES AND USES THEREOF | Ascendis Pharma Oncology Division A/S (DK) | 2023-06-08 | — | — | US | disclosed |
| US-20210040244-A1 | p-BORONOPHENYLALANINE DERIVATIVE AND COMPOSITION CONTAINING SAME, AND KIT FOR PRODUCING SAID DERIVATIVE AND COMPOSITION | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2021-02-11 | — | — | US | disclosed |
| CN-111979777-A | Durable colorless moisture absorption and sweat releasing composite finishing agent and preparation method thereof | 多恩生物科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019163790-A1 | p-BORONOPHENYLALANINE DERIVATIVE AND COMPOSITION CONTAINING SAME, AND KIT FOR PRODUCING SAID DERIVATIVE AND COMPOSITION | 国立大学法人東京工業大学 | 2019-08-29 | — | — | WO | disclosed |
| US-20190224329-A1 | Incremental Dose Finding in Controlled-Release PTH Compounds | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2019-07-25 | — | — | US | disclosed |
| US-20180214387-A1 | AQUEOUS SOLUTION COMPRISING A POLYPHENOL | OPTERION HEALTH AG (CH) | 2018-08-02 | — | — | US | disclosed |
| US-10035970-B2 | Friction-reducing compound, method of producing same, and lubricant composition | BASF SE (DE) | 2018-07-31 | — | — | US | disclosed |
| US-20170321147-A1 | Friction-Reducing Compound, Method of Producing Same, and Lubricant Composition | BASF SE (DE) | 2017-11-09 | — | — | US | disclosed |
| US-7897647-B2 | Useful in extending the in vivo circulating life of biologically active materials; bicine linker allows for the manipulation of the hydrolysis rate of the prodrug, thereby releasing the native entities at various rates in vivo as well as in vitro | ENZON PHARMACEUTICALS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7858792-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7858792-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7569588-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569588-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20090176767-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE BIOPHARMA R&D IP, LLC | 2009-07-09 | — | — | US | disclosed |
| US-20090176767-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE BIOPHARMA R&D IP, LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190224329-A1 | Incremental Dose Finding in Controlled-Release PTH Compounds | PTH1R, CALCA, CALCB | ALOX15 3040/4885KDM4E 4541/4885MAPT 2668/4885 |
| US-20210040244-A1 | p-BORONOPHENYLALANINE DERIVATIVE AND COMPOSITION CONTAINING SAME, AND KIT FOR PRODUCING SAID DERIVATIVE AND COMPOSITION | KIT, SETD7, PAH | ALOX15 3838/4885KDM4E 336/4885MAPT 1794/4885 |
| US-20180214387-A1 | AQUEOUS SOLUTION COMPRISING A POLYPHENOL | SORD, AQP1, SI | ALOX15 1113/4885KDM4E 3435/4885MAPT 396/4885 |
| US-20090176767-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM1, CHRM3 | ALOX15 3326/4885KDM4E 2122/4885MAPT 4624/4885 |
| US-20230174605-A1 | IL-2 SEQUENCES AND USES THEREOF | IL2, IL2RA, IL4I1 | ALOX15 1535/4885KDM4E 3060/4885MAPT 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.