Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.35 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.35 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159490 | 0.95 | CASP1 (0.48) | CASP1CASP3CASP6CASP8MMP1 | |
| SCHEMBL6158140 | 0.88 | CASP1 (0.51) | CASP1KMT2AALDH1A1HPGDCASP3 | |
| SCHEMBL6158311 | 0.85 | CASP1 (0.55) | CASP1KMT2AALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL6158942 | 0.83 | CASP1 (0.54) | CASP1CASP3CASP6CASP8MMP1 | |
| SCHEMBL6158658 | 0.83 | CASP1 (0.46) | CASP1ALDH1A1EPHX2KCNA5PSMB11 | |
| SCHEMBL6157498 | 0.83 | CASP1 (0.47) | CASP1PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL6159126 | 0.82 | CASP1 (0.47) | CASP1KCNA5 | |
| SCHEMBL6157776 | 0.82 | CASP1 (0.48) | CASP1CASP3CASP6OPRM1 | |
| SCHEMBL6158329 | 0.81 | CASP1 (0.58) | CASP1KMT2AALDH1A1HPGDCASP3 | |
| SCHEMBL6158910 | 0.79 | CASP1 (0.52) | CASP1CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |