SCHEMBL6158474

SCHEMBL6158474

COCOc1ccc(CON)cc1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 16/20 0.64
AGXT P21549 10/20 0.64
CYP3A4 P08684 2/20 0.47
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14341660 0.85 APP (0.47) IDO1AGXTMAOB
SCHEMBL3589633 0.80 NQO1 (0.50) MAOB
SCHEMBL15143758 0.79 MAOB (0.58) MAOB
SCHEMBL17553700 0.79 NQO1 (0.40) IDO1AGXTMAOB
SCHEMBL1520099 0.79 IDO1 (1.00) IDO1AGXTCYP3A4MAOB
SCHEMBL25986811 0.79 LTA4H (0.50)
Hydrochloric Acid SCHEMBL501912 0.77 IDO1 (1.00) IDO1AGXTCYP3A4MAOB
SCHEMBL2127451 0.77 SMN1; SMN2 (0.47) MAOB
SCHEMBL6167562 0.76 TAAR1 (0.64) MAOB
SCHEMBL26317278 0.76 AGXT (0.76) IDO1AGXTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6924300-B2 Oxyiminoalkanoic acid derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
EP-1023426-B1 LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS PROCTER & GAMBLE (US) 2005-02-09 EP disclosed
EP-1023431-B1 HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS PROCTER & GAMBLE (US) 2004-12-15 EP disclosed
EP-1077957-B1 OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-08-04 EP disclosed
EP-1428531-A1 Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-06-16 EP disclosed
CN-1148361-C Oxyiminoalkanoic acid derivatives ����ҩƷ��ҵ��ʽ���� 2004-05-05 CN disclosed
US-20030186985-A1 Oxyiminoalkanoic acid derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-10-02 US disclosed
US-6495581-B1 DRUG FOR TREATING DIABETES MELLITUS, HYPERLIPEMIA, IMPAIRED GLUCOSE TOLERANCE, ARTERIAL SCLEROSIS AND IMPROVING INSULIN RESISTANCE, INFLAMMATORY DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-12-17 US disclosed
US-6335312-B1 BRANCHED C10-18 ALKYL ENDCAPPED ETHYLENE OXIDE-PROPYLENE OXIDE POLYETHERS TERMINATED WITH A HYDROXY GROUP THAT IS OPTIONALLY SULFATED THE PROCTER & GAMBLE COMPANY 2002-01-01 US disclosed
US-6281181-B1 Light-duty liquid or gel dishwashing detergent compositions comprising mid-chain branched surfactants THE PROCTER & GAMBLE COMPANY 2001-08-28 US disclosed
WO-1999018929-A9 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS PROCTER & GAMBLE (US) 1999-08-26 WO disclosed
WO-1999019448-A1 HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019449-A1 HARD SURFACE CLEANING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019435-A1 GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019450-A1 AQUEOUS AND NON-AQUEOUS HEAVY DUTY LIQUID DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019439-A1 LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019440-A1 LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999019434-A1 GRANULAR DETERGENT COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999018928-A1 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed
WO-1999018929-A1 PERSONAL CLEANSING COMPOSITIONS COMPRISING MID-CHAIN BRANCHED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1999-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186985-A1 Oxyiminoalkanoic acid derivatives GPR119, IRS1, CPT1A IDO1 2988/4885AGXT 397/4885CYP3A4 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.