Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509270 | 0.90 | CYP2A6 (0.44) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL3589633 | 0.85 | NQO1 (0.50) | MAPTNQO1TDP1MAOB | |
| SCHEMBL25986811 | 0.84 | LTA4H (0.50) | SMN1; SMN2LMNAALDH1A1NQO1L3MBTL1 | |
| SCHEMBL2128463 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1NPC1NQO1L3MBTL1 | |
| SCHEMBL27387850 | 0.82 | CYP1A2 (0.52) | SMN1; SMN2LMNAALDH1A1MAPTNPC1 | |
| SCHEMBL14341660 | 0.82 | APP (0.47) | SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL27504104 | 0.82 | NQO1 (0.50) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL6160052 | 0.80 | FYN (0.47) | SMN1; SMN2NPC1RAB9ANQO1KMT2A | |
| SCHEMBL3473670 | 0.80 | APP (0.37) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL7855924 | 0.80 | APP (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ANQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390731-A1 | MANIPULATION OF THE RETINOIC ACID SIGNALING PATHWAY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-12-17 | — | — | US | disclosed |
| US-10838303-B2 | Resist underlayer film forming composition for lithography containing hydrolyzable silane having carbonate skeleton | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| EP-3222688-A1 | FILM-FORMING COMPOSITION CONTAINING CROSSLINKABLE REACTIVE SILICONE | Nissan Chemical Industries, Ltd. (JP) | 2017-09-27 | — | — | EP | disclosed |
| US-9449732-B2 | Charge transport film, method for producing the same, and light-emitting element and photoelectric conversion element using the same | FUJIFILM CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| CN-102471355-B | Diphenyl sulfide derivatives and drugs containing the same as the active ingredient | KYORIN PHARMACEUTICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| EP-2452944-B1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING THEM AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-8569270-B2 | Diphenyl sulfide derivatives and medicines containing same as active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20120238774-A1 | CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME | FUJIFILM CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
| CN-102471355-A | Diphenyl sulfide derivatives and drugs containing the same as the active ingredient | KYORIN SEIYAKU KK | 2012-05-23 | — | — | CN | disclosed |
| EP-2452944-A1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-7160667-B2 | Novolak phenolic resin, quaternary heterocyclic amine, and -onium or ammonium photo-thermal converting agents; positive planographic printing plate precursor; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5385914-A | Cardiotonic carbostyril agents for treating heart ailments | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0355583-B1 | Cardiotonics | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5266577-A | Method of treating congestive heart failure using carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5198448-A | Cardiovascular disorders | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5053514-A | Side effect reduction; carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238774-A1 | CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME | PCTP, CDH1, PLTP | SMN1; SMN2 4249/4885LMNA 1221/4885ALDH1A1 4057/4885 |
| US-20200390731-A1 | MANIPULATION OF THE RETINOIC ACID SIGNALING PATHWAY | RARB, RARA, RARG | SMN1; SMN2 1958/4885LMNA 1684/4885ALDH1A1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.