Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159352 | 0.91 | HCRTR2 (0.48) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6162691 | 0.88 | HCRTR2 (0.48) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6157202 | 0.87 | HCRTR1 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL6157886 | 0.85 | HCRTR2 (0.49) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6160856 | 0.85 | HCRTR2 (0.49) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6160749 | 0.82 | HCRTR2 (0.53) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6158799 | 0.81 | HCRTR2 (0.52) | HCRTR2HCRTR1CCR8KMT2AGAA | |
| SCHEMBL6159008 | 0.80 | HCRTR1 (0.55) | HCRTR2HCRTR1KMT2AGAA | |
| SCHEMBL6160316 | 0.80 | HCRTR2 (0.53) | HCRTR2HCRTR1KMT2AGAAMEN1 | |
| SCHEMBL6158906 | 0.80 | ALDH1A1 (0.48) | HCRTR2HCRTR1CCR8KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953789-B2 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-10-11 | — | — | US | disclosed |
| US-20040157894-A1 | Thiol compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| US-6420415-B1 | Thiol compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1132379-A1 | NOVEL THIOL DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157894-A1 | Thiol compounds, their production and use | TST, SULT1E1, QSOX1 | HCRTR2 1754/4885HCRTR1 1930/4885CCR8 2247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.