Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084813 | 0.84 | PDCD1 (0.39) | PDCD1CD274ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL4623138 | 0.84 | PDCD1 (0.39) | PDCD1CD274ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6890691 | 0.83 | PDCD1 (0.38) | PDCD1CD274KDM4ECHRNB2CHRNA4 | |
| SCHEMBL3998331 | 0.83 | PDCD1 (0.38) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7110286 | 0.83 | PDCD1 (0.38) | PDCD1CD274KDM4ECHRNB2CHRNA4 | |
| SCHEMBL8503531 | 0.82 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL8679512 | 0.82 | PDCD1 (0.37) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL27478943 | 0.82 | PDCD1 (0.40) | PDCD1CD274ALDH1A1KDM4ECHRNB2 | |
| SCHEMBL5836290 | 0.81 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL1241178 | 0.81 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501843-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091265-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-06 | — | — | WO | disclosed |