Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 4/20 | 0.31 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157940 | 0.90 | CASP1 (0.72) | CASP1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6159902 | 0.88 | CASP1 (0.43) | CASP1 | |
| SCHEMBL6160564 | 0.84 | CASP1 (0.80) | CASP1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL6159166 | 0.82 | CASP1 (0.60) | CASP1EDNRAEDNRBKDM4EHPGD | |
| SCHEMBL6158942 | 0.78 | CASP1 (0.54) | CASP1 | |
| SCHEMBL7425857 | 0.78 | CASP1 (0.41) | CASP1 | |
| SCHEMBL6158910 | 0.78 | CASP1 (0.52) | CASP1 | |
| SCHEMBL6159608 | 0.77 | CASP1 (0.43) | CASP1 | |
| SCHEMBL6158140 | 0.77 | CASP1 (0.51) | CASP1HPGDKMT2A | |
| SCHEMBL6159199 | 0.77 | CASP1 (0.54) | CASP1KDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |