Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 6/20 | 0.62 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060824 | 1.00 | PTAFR (0.62) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL7060832 | 1.00 | PTAFR (0.62) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL6159663 | 1.00 | PTAFR (0.62) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL6159652 | 1.00 | PTAFR (0.62) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL6822928 | 0.82 | PTAFR (0.69) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL13414990 | 0.77 | ACHE (0.54) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL11101046 | 0.77 | ACHE (0.58) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL10456245 | 0.77 | PTAFR (1.00) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL7018006 | 0.77 | PTAFR (1.00) | PTAFRACHEPTPN1MEN1KMT2A | |
| SCHEMBL7018004 | 0.77 | PTAFR (1.00) | PTAFRACHEPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032713-A1 | Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-10 | — | — | US | claimed |
| US-20040028756-A1 | Platelet-activated factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-12 | — | — | US | claimed |
| WO-2003082199-A2 | PLATELET-ACTIVATING FACTOR ANTAGONISTS AS ANALGESIC, ANTI-INFLAMMATORY, UTERINE CONTRACTION INHIBITING, AND ANTI-TUMOR AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-10-09 | — | — | WO | claimed |
| US-20050032713-A1 | Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-10 | — | — | US | disclosed |
| US-20040028756-A1 | Platelet-activated factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-12 | — | — | US | disclosed |
| WO-2003082199-A2 | PLATELET-ACTIVATING FACTOR ANTAGONISTS AS ANALGESIC, ANTI-INFLAMMATORY, UTERINE CONTRACTION INHIBITING, AND ANTI-TUMOR AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-10-09 | — | — | WO | disclosed |
| EP-0875247-B1 | Method for controlling the plasma level of lipoproteins | TNO (NL) | 2003-05-28 | — | — | EP | disclosed |
| US-6444664-B1 | ANTAGONIST OF PLATELET ACTIVATING FACTOR; BENZO- OR THIENOTRIAZOLO-DIAZEPINE OR BENZODIAZEPINE DERIVATIVE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST - NATUURWETEN SCHAPPELIJK ONDERZOEK (TNO) (NL) | 2002-09-03 | — | — | US | disclosed |
| EP-0875247-A1 | Method for controlling the plasma level of lipoproteins | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1998-11-04 | — | — | EP | disclosed |
| US-5631246-A | INCREASING LEVELS OF VON WILLEBRAND FACTOR AND/OR BLOOD FACTOR VIII | THE CANADIAN RED CROSS SOCIETY (CA) | 1997-05-20 | — | — | US | disclosed |