Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624514 | 1.00 | NOS3 (0.46) | NOS3NOS2ADRB1ADRB2NPSR1 | |
| SCHEMBL34460138 | 0.84 | KIF11 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL29304997 | 0.79 | NOS3 (0.46) | NOS3NOS2ADRB1ADRB2NPSR1 | |
| SCHEMBL28726473 | 0.79 | NOS3 (0.48) | NOS3NOS2ADRB1ADRB2NPSR1 | |
| SCHEMBL24566340 | 0.77 | OGA (0.35) | GRM5 | |
| SCHEMBL23484580 | 0.76 | BACE1 (0.36) | GRM5CTSSGABRA1GABRG2GABRB3 | |
| SCHEMBL6161979 | 0.74 | NOS3 (0.52) | NOS3NOS2ADRB1ADRB2NPSR1 | |
| SCHEMBL2334808 | 0.74 | NOS3 (0.52) | NOS3NOS2ADRB1ADRB2MAPK1 | |
| SCHEMBL20448716 | 0.74 | NOS3 (0.52) | NOS3NOS2ADRB1ADRB2NPSR1 | |
| SCHEMBL29624440 | 0.74 | NOS3 (0.52) | NOS3NOS2ADRB1ADRB2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-10-24 | — | — | US | disclosed |
| US-10377737-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20180290986-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-10-11 | — | — | US | disclosed |
| EP-3385254-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE/ACARICIDE HAVING SAID DERIVATIVE AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20050143578-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1434772-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2005-05-04 | — | — | EP | disclosed |
| US-20040192914-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | disclosed |
| EP-1434772-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031434-A1 | COMPOUNDS AND METHODS | SMITH KLINE BEECHAM CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192914-A1 | Compounds and methods | METAP2, METAP1, DNPEP | NOS3 84/4885NOS2 54/4885ADRB1 3182/4885 |
| US-20180290986-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | AADAC, CYP51A1, NAT1 | NOS3 314/4885NOS2 943/4885ADRB1 1943/4885 |
| US-10377737-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | AADAC, CYP51A1, NAT1 | NOS3 314/4885NOS2 943/4885ADRB1 1943/4885 |
| US-20050143578-A1 | Compounds and methods | METAP2, METAP1, DNPEP | NOS3 99/4885NOS2 43/4885ADRB1 3164/4885 |
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | AADAC, CYP51A1, NAT1 | NOS3 314/4885NOS2 943/4885ADRB1 1943/4885 |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | AADAC, CYP51A1, NAT1 | NOS3 314/4885NOS2 943/4885ADRB1 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.