Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7328045 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| Hydrochloric Acid SCHEMBL7328249 | 0.80 | APOBEC3A (0.57) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| SCHEMBL8989176 | 0.78 | CHRM2 (0.55) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| SCHEMBL4754210 | 0.77 | KDM4E (1.00) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| Hydrochloric Acid SCHEMBL7333899 | 0.77 | APOBEC3A (0.56) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| SCHEMBL7334983 | 0.77 | MEN1 (0.60) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| SCHEMBL28298203 | 0.76 | CHRM2 (0.79) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| Hydrochloric Acid SCHEMBL7326029 | 0.76 | MEN1 (0.58) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| SCHEMBL6159814 | 0.76 | LMNA (0.88) | LMNASMN1; SMN2KDM4EHTTCHRM2 | |
| Hydrochloric Acid SCHEMBL8989118 | 0.76 | ALDH1A1 (0.63) | LMNASMN1; SMN2KDM4EHTTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |