Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159949 | 1.00 | FAAH (0.35) | FAAHLPAR3LPAR1PLA2G10PPARG | |
| SCHEMBL6161870 | 0.96 | PPARG (0.33) | PPARGALDH1A1HPGDEPHX2 | |
| SCHEMBL6159794 | 0.96 | PPARG (0.33) | PPARGALDH1A1HPGDEPHX2 | |
| SCHEMBL6160633 | 0.96 | PPARG (0.33) | PPARGALDH1A1HPGDEPHX2 | |
| SCHEMBL6160375 | 0.92 | LPAR3 (0.38) | FAAHLPAR3LPAR1EPHX2 | |
| SCHEMBL6160389 | 0.92 | LPAR3 (0.38) | FAAHLPAR3LPAR1EPHX2 | |
| SCHEMBL6161001 | 0.88 | ENPP2 (0.35) | ALDH1A1HPGD | |
| SCHEMBL6166944 | 0.88 | HPGD (0.33) | LPAR3LPAR1HPGD | |
| SCHEMBL6161220 | 0.88 | HPGD (0.33) | LPAR3LPAR1HPGD | |
| SCHEMBL6162169 | 0.88 | HPGD (0.33) | LPAR3LPAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |