Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268867 | 0.85 | MAPT (0.65) | MAPTPOLBKDM4EHTTALDH1A1 | |
| SCHEMBL5629195 | 0.85 | SMN1; SMN2 (0.60) | MAPTPOLBKDM4EATMHTT | |
| SCHEMBL17085330 | 0.85 | PKM (0.68) | MAPTPOLBKDM4EATMHTT | |
| SCHEMBL1531297 | 0.84 | MAPT (1.00) | MAPTHTTCTSVCTSLALDH1A1 | |
| SCHEMBL17434413 | 0.84 | ALDH1A1 (0.54) | MAPTKDM4EHTTPKMCTSV | |
| SCHEMBL19669453 | 0.84 | MAPT (0.51) | MAPTPOLBKDM4EHTTPKM | |
| SCHEMBL17434169 | 0.84 | SMN1; SMN2 (0.59) | MAPTPOLBHTTPKMCTSV | |
| SCHEMBL1403472 | 0.83 | ALDH1A1 (0.56) | MAPTPOLBKDM4EHTTPKM | |
| SCHEMBL30203403 | 0.83 | ALDH1A1 (0.56) | MAPTPOLBKDM4EHTTPKM | |
| SCHEMBL9068677 | 0.82 | ALDH1A1 (0.54) | MAPTPOLBKDM4EHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |