SCHEMBL616075

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10188831	0.88	PDGFRB (0.41)	SYKGAKPDGFRBPDGFRAPTGS2
	SCHEMBL616536	0.80	CCNC (0.39)	PTGS2NPC1RAB9A
	SCHEMBL615529	0.79	GAK (0.46)	GAKPTGS2EPHB4TUBB4ATUBB
	SCHEMBL618142	0.79	NPC1 (0.48)	SYKPTGS2JAK2JAK1TYK2
	SCHEMBL16471430	0.78	PTGS2 (0.48)	PTGS2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL617751	0.78	POLB (0.55)	PDGFRBEPHB4TUBB4ATUBBTUBA3C
	SCHEMBL618456	0.78	MAPK1 (0.52)	PDGFRBPTGS2EPHB4
	SCHEMBL1167718	0.77	SYK (0.50)	SYKGAKPDGFRBPDGFRAJAK2
	SCHEMBL615671	0.77	SYK (0.50)	SYKGAKPDGFRBPDGFRAJAK2
	SCHEMBL615932	0.77	PTGS2 (0.52)	GAKPDGFRBPDGFRAPTGS2TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.