Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 9/20 | 0.52 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | UGCG | Q16739 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160779 | 1.00 | GHSR (0.52) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6160305 | 0.92 | GHSR (0.51) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6164572 | 0.92 | GHSR (0.52) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6160303 | 0.92 | GHSR (0.51) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6164577 | 0.92 | GHSR (0.52) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| Hydrochloric Acid SCHEMBL6164015 | 0.91 | GHSR (0.51) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| Hydrochloric Acid SCHEMBL6164009 | 0.91 | GHSR (0.51) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6162501 | 0.88 | PPARA (0.42) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6162496 | 0.88 | PPARA (0.42) | GHSRCCKBRHCRTR2CYP3A4UGCG | |
| SCHEMBL6160934 | 0.85 | KCNA1 (0.55) | GHSRCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |