Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162501 | 1.00 | PPARA (0.42) | PPARAHCRTR2GHSRCTSSCCKBR | |
| SCHEMBL8413200 | 0.93 | PPARA (0.43) | PPARAHCRTR2GHSRCTSSCCKBR | |
| SCHEMBL6162692 | 0.89 | NR1H2 (0.48) | PPARAHCRTR2GHSRCTSSHCRTR1 | |
| SCHEMBL6162688 | 0.89 | NR1H2 (0.48) | PPARAHCRTR2GHSRCTSSHCRTR1 | |
| SCHEMBL6160785 | 0.88 | GHSR (0.52) | HCRTR2GHSRCCKBRUGCGCYP3A4 | |
| SCHEMBL6160779 | 0.88 | GHSR (0.52) | HCRTR2GHSRCCKBRUGCGCYP3A4 | |
| SCHEMBL6162216 | 0.87 | KCNA1 (0.48) | PPARAHCRTR2GHSRCTSSCCKBR | |
| SCHEMBL6166160 | 0.86 | CCKBR (0.44) | PPARAHCRTR2GHSRCTSSCCKBR | |
| SCHEMBL6166156 | 0.86 | CCKBR (0.44) | PPARAHCRTR2GHSRCTSSCCKBR | |
| SCHEMBL6163229 | 0.86 | DRD2 (0.44) | PPARAHCRTR2GHSRCTSSHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991638-B1 | NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-08-17 | — | — | EP | claimed |
| EP-1175419-B1 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-05-28 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |