Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 5/20 | 0.50 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054667 | 0.82 | PARP1 (0.53) | MEP1BPARP1FOLH1KDM1AMAOA | |
| SCHEMBL2426602 | 0.80 | AKR1B1 (0.54) | MEP1BPARP1FOLH1PLA2G10PLA2G2A | |
| SCHEMBL19510176 | 0.80 | MEP1B (1.00) | MEP1BMEP1A | |
| SCHEMBL6160793 | 0.79 | HDAC8 (0.60) | MEN1KMT2AHDAC8HDAC6MAOA | |
| SCHEMBL3048724 | 0.79 | PARP1 (0.53) | MEP1BPARP1FOLH1F10 | |
| SCHEMBL6030006 | 0.79 | HTR3E (0.58) | MEP1BPARP1FOLH1F10 | |
| SCHEMBL9405490 | 0.79 | PARP1 (0.53) | MEP1BPARP1FOLH1KDM1AMAOA | |
| SCHEMBL2635907 | 0.78 | HDAC6 (0.59) | MEP1BMEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL24031215 | 0.78 | SLC7A5 (0.56) | MEP1BPARP1F10 | |
| SCHEMBL3451761 | 0.78 | SLC7A5 (0.56) | MEP1BPARP1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |