Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GLS | O94925 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | AOC2 | O75106 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522983 | 0.86 | HDAC1 (0.65) | HDAC8HDAC6MEN1KMT2AGLS | |
| SCHEMBL27208476 | 0.85 | AOC2 (0.59) | HDAC8HDAC6MEN1KMT2AGLS | |
| SCHEMBL1634793 | 0.84 | GLS (0.52) | HDAC8HDAC6MEN1KMT2AGLS | |
| SCHEMBL11627613 | 0.81 | GLS (0.50) | MEN1KMT2AGLSROCK1MAOA | |
| SCHEMBL1632800 | 0.80 | GLS (0.49) | MEN1KMT2AGLSROCK1 | |
| SCHEMBL11627168 | 0.80 | CA1 (0.54) | GLSROCK1MAOAMAOBAOC2 | |
| SCHEMBL11625886 | 0.80 | ALDH1A1 (0.59) | HDAC8HDAC6MEN1KMT2AHDAC1 | |
| SCHEMBL10160138 | 0.80 | EPHX2 (0.69) | HDAC8HDAC6MEN1KMT2AGLS | |
| SCHEMBL11627073 | 0.80 | EPHX2 (0.58) | KMT2AGLS | |
| SCHEMBL2507987 | 0.80 | GLS (0.49) | MEN1KMT2AGLSROCK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |