Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162632 | 0.84 | NR1H4 (0.53) | NR1H4 | |
| SCHEMBL6158927 | 0.83 | NR1H4 (0.51) | NR1H4 | |
| SCHEMBL6160198 | 0.80 | — | — | |
| SCHEMBL6160584 | 0.79 | — | — | |
| SCHEMBL6158419 | 0.79 | — | — | |
| SCHEMBL6161056 | 0.78 | — | — | |
| SCHEMBL27569502 | 0.77 | NR1H4 (0.53) | NR1H4CA12CA2CA9 | |
| SCHEMBL6159494 | 0.77 | CCKBR (0.68) | — | |
| SCHEMBL6161018 | 0.73 | RAB9A (0.39) | — | |
| SCHEMBL6160987 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| CN-1325385-A | Gastrin and cholecystokinin receptor ligands | BLACK JAMES FOUNDATION (GB) | 2001-12-05 | — | — | CN | disclosed |