Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468186 | 0.90 | P2RX7 (0.53) | P2RX7SIGMAR1 | |
| SCHEMBL6170302 | 0.85 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL6163189 | 0.81 | HTR2C (0.57) | SIGMAR1 | |
| SCHEMBL7681242 | 0.81 | P2RX7 (0.55) | P2RX7SIGMAR1 | |
| SCHEMBL6164191 | 0.80 | HTR1A (0.57) | P2RX7 | |
| Hydrochloric Acid SCHEMBL7673708 | 0.80 | P2RX7 (0.54) | P2RX7SIGMAR1 | |
| SCHEMBL6783014 | 0.80 | HTR2A (0.42) | — | |
| SCHEMBL7672812 | 0.80 | P2RX7 (0.56) | P2RX7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7675560 | 0.79 | P2RX7 (0.55) | P2RX7SIGMAR1 | |
| SCHEMBL7678668 | 0.77 | P2RX7 (0.51) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060163-B1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE CO CHEM PHARM FAB (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-6903118-B1 | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides | KLINGE PHARMA GMBH (DE) | 2005-06-07 | — | — | US | disclosed |