Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307050 | 0.89 | KDM4E (0.53) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| Hydrochloric Acid SCHEMBL15954729 | 0.88 | KDM4E (0.51) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| Hydrochloric Acid SCHEMBL6928280 | 0.88 | KDM4E (0.51) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| SCHEMBL161226 | 0.87 | KDM4E (0.50) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| SCHEMBL3376199 | 0.84 | ADRA1A (0.49) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| Trifluoroacetic Acid SCHEMBL3954282 | 0.83 | HDAC3 (0.44) | KDM4EMEN1KMT2APTGDR2RBP4 | |
| Trifluoroacetic Acid SCHEMBL5189043 | 0.82 | PTGDR2 (0.46) | PTGDR2RBP4HDAC3HDAC1PTPN5 | |
| SCHEMBL161548 | 0.81 | ADRA1A (0.51) | KDM4EMEN1MAPTKMT2ATP53 | |
| SCHEMBL28212021 | 0.81 | ADRA1A (0.51) | KDM4EMEN1MAPTKMT2ATP53 | |
| SCHEMBL6383642 | 0.81 | ADRA1A (0.51) | KDM4EMEN1MAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040972-A1 | DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS | GOBBI LUCA (CH) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040972-A1 | DUAL MODULATORS OF 5HT2A AND D3 RECEPTORS | HTR2A, HTR3A, HTR1A | KDM4E 2551/4885MEN1 3327/4885MAPT 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.