SCHEMBL616119

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL615800	0.93	PTGS2 (0.45)	PTGS2GAKPOLQ
	SCHEMBL16471441	0.90	PTGS2 (0.43)	PTGS2MEN1USP2GAAMAPT
	SCHEMBL617393	0.90	PTGS2 (0.49)	PTGS2FYNPOLQMEN1HTT
	SCHEMBL616140	0.82	PTGS2 (0.51)	PTGS2GAKCYP19A1GAAHSD17B10
	SCHEMBL618806	0.82	PTGS2 (0.51)	PTGS2GAKGAAMAPT
	SCHEMBL616590	0.82	PTGS2 (0.53)	PTGS2MEN1LMNAMAPTHTT
	SCHEMBL619367	0.82	PTGS2 (0.69)	PTGS2LMNA
	SCHEMBL617540	0.82	PTGS2 (0.51)	PTGS2GABRA1GABRB2ALOX5
	SCHEMBL617559	0.82	PTGS2 (0.54)	PTGS2MEN1LMNAGAAMAPT
	SCHEMBL616047	0.81	PTGS2 (0.51)	PTGS2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.