SCHEMBL616590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL619367	0.88	PTGS2 (0.69)	PTGS2PDGFRBPDGFRAALDH1A1LMNA
	SCHEMBL16471418	0.87	PTGS2 (0.51)	PTGS2ALDH1A1MAPTKDM4ESMN1; SMN2
	SCHEMBL616047	0.87	PTGS2 (0.51)	PTGS2PDGFRBPDGFRAKIT
	SCHEMBL617805	0.87	PTGS2 (0.59)	PTGS2MAPTSMN1; SMN2KITLMNA
	SCHEMBL616247	0.87	PTGS2 (0.51)	PTGS2ALDH1A1MAPTKDM4ENPC1
	SCHEMBL617994	0.87	PTGS2 (0.50)	PTGS2PDGFRBPDGFRAALDH1A1MAPT
	SCHEMBL617393	0.85	PTGS2 (0.49)	PTGS2MEN1HTTKMT2A
	SCHEMBL618571	0.85	PTGS2 (0.49)	PTGS2PDGFRBPDGFRAALDH1A1MAPT
	SCHEMBL14537135	0.83	PTGS2 (0.48)	PTGS2ALDH1A1MAPTKDM4EMEN1
	SCHEMBL617559	0.82	PTGS2 (0.54)	PTGS2ALDH1A1MAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.