Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159879 | 0.86 | ALDH1A1 (0.40) | EPHX2ALDH1A1KMT2APDE1C | |
| SCHEMBL6158707 | 0.81 | — | — | |
| SCHEMBL6160554 | 0.80 | FKBP1A (0.39) | EPHX2ALDH1A1KMT2AFKBP1A | |
| SCHEMBL6163519 | 0.78 | — | — | |
| SCHEMBL6159838 | 0.78 | PPARG (0.39) | — | |
| SCHEMBL7080456 | 0.77 | — | — | |
| SCHEMBL6330062 | 0.76 | EPHX2 (0.37) | EPHX2KMT2A | |
| SCHEMBL6164287 | 0.74 | EPHX2 (0.34) | EPHX2ALDH1A1KMT2AFKBP1A | |
| SCHEMBL7085195 | 0.73 | P2RX7 (0.39) | — | |
| SCHEMBL6160412 | 0.73 | CYP19A1 (0.40) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |