SCHEMBL6161330

SCHEMBL6161330

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1ccc(Cl)c(N)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
NPSR1 Q6W5P4 5/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ACACB O00763 1/20 0.40
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPT P10636 4/20 0.37
LMNA P02545 4/20 0.37
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
HTT P42858 2/20 0.35
UBE2N P61088 2/20 0.35
GLA P06280 1/20 0.35
MITF O75030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044353 0.89 MEN1 (0.41) RAB9AMEN1KMT2ANPSR1ALDH1A1
SCHEMBL10959215 0.87 MEN1 (0.42) RAB9AMEN1KMT2ANPSR1ALDH1A1
SCHEMBL11772726 0.85 SMN1; SMN2 (0.45) NPC1RAB9AMEN1KMT2ANPSR1
SCHEMBL9814164 0.85 KMT2A (0.40) RAB9AMEN1KMT2ANPSR1ALDH1A1
SCHEMBL11514547 0.84 MAPK1 (0.43) RAB9AMEN1KMT2ANPSR1ALDH1A1
SCHEMBL9868418 0.84 NPSR1 (0.48) NPC1RAB9AMEN1KMT2ANPSR1
SCHEMBL6163087 0.84 NPC1 (0.41) NPC1RAB9AMEN1KMT2ANPSR1
SCHEMBL11817386 0.84 MEN1 (0.41) MEN1KMT2ANPSR1ALDH1A1MAPK1
SCHEMBL11002253 0.83 NPSR1 (0.43) RAB9AMEN1KMT2ANPSR1ALDH1A1
SCHEMBL7767160 0.83 NPSR1 (0.45) NPC1RAB9AMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711758-B1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO LTD (JP) 2005-01-26 EP disclosed
EP-1020450-B1 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound and process for preparation thereof FUJI PHOTO FILM CO LTD (JP) 2004-02-11 EP disclosed
EP-1020450-A1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 2000-07-19 EP disclosed
EP-0508398-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-07-01 EP disclosed
EP-0503587-B1 Silver halide colour photographic material FUJI PHOTO FILM CO LTD (JP) 1998-06-24 EP disclosed
US-5672714-A HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1997-09-30 US disclosed
EP-0447969-B1 Yellow dye-forming coupler and silver halide color photographic material containing same FUJI PHOTO FILM CO LTD (JP) 1997-01-15 EP disclosed
US-5585227-A CONTAINING SPECIFIED YELLOW DYE-FORMING COUPLER AND CYAN COUPLER; REDUCED STAINING DURING PROCESSING AND STORAGE FUJI PHOTO FILM CO., LTD. (JP) 1996-12-17 US disclosed
EP-0711758-A2 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 1996-05-15 EP disclosed
US-5514531-A ACYLACETAMIDE YELLOW DYE COUPLERS FOR COLORFASTNESS IN PHOTOGRAPHIC FILMS FUJI PHOTO FILM CO., LTD. (JP) 1996-05-07 US disclosed
US-5250406-A Sharpness, color reproduction, stability FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0508398-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-10-14 EP disclosed
EP-0503658-A1 Silver halide colour photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0503587-A1 Silver halide colour photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0486965-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-05-27 EP disclosed
EP-0447969-A1 Yellow dye-forming coupler and silver halide color photographic material containing same FUJI PHOTO FILM CO., LTD. (JP) 1991-09-25 EP disclosed
US-4587210-A COLORFASTNESS; DISCOLORATION INHIBITION; MAGENTA COUPLERS; WHITE BACKGROUND FUJI PHOTO FILM CO., LTD. (JP) 1986-05-06 US disclosed
US-4254208-A DISPERSION, LIQUEFYING, SOLIDS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
US-4106942-A COMPOUNDS CONTAINING SULFIDE, KETONE, AND AMIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1978-08-15 US disclosed
US-4031130-A Aliphatic β-keto esters AGFA-GEVAERT, A.G. (DT) 1977-06-21 US disclosed