SCHEMBL7044353

SCHEMBL7044353

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1ccc(Cl)c([NH])c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
NPSR1 Q6W5P4 6/20 0.41
MAPK1 P28482 5/20 0.41
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ACACB O00763 1/20 0.40
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPT P10636 6/20 0.37
LMNA P02545 3/20 0.37
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
HTT P42858 3/20 0.35
UBE2N P61088 2/20 0.35
GLA P06280 1/20 0.35
MITF O75030 1/20 0.35
RORC P51449 3/20 0.33
PDK1 Q15118 1/20 0.33
RAD52 P43351 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6161330 0.89 NPC1 (0.43) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL11514545 0.84 SMN1; SMN2 (0.43) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL9848197 0.84 SMN1; SMN2 (0.44) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL9868418 0.84 NPSR1 (0.48) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL6163087 0.84 NPC1 (0.41) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL11817386 0.84 MEN1 (0.41) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL11002253 0.83 NPSR1 (0.43) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL11772726 0.83 SMN1; SMN2 (0.45) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL7767160 0.83 NPSR1 (0.45) MEN1KMT2ANPSR1MAPK1ALDH1A1
SCHEMBL8622225 0.83 NPSR1 (0.41) MEN1KMT2ANPSR1MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
EP-0763774-B1 Process for preparation of 2-equivalent 4-arylthio-5-pyrazolone magenta couplers TULALIP CONSULTORIA COM SOCIED (PT) 2003-04-02 EP disclosed
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
EP-0651289-B1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
US-5646297-A REACTING DIARYLSULFIDE AND 4-EQUIVALENT-5-PYRAZOLONE IN PRESENCE OF 1,8-DIAZABICYCLO-(5,4,0)-UNDECEN-7-ENE IN SOLVENT; SULFIDING IMATION CORP. (US) 1997-07-08 US disclosed
US-5641613-A SUPPORT BEARING LIGHT SENSITIVE SILVER HALIDE LAYER CONTAINING BICYCLIC AZOLE COUPLER, AZOPYRAZOLONE MASKING COUPLER, LOW IMPACT DEVELOPMENT INHIBITOR RELEASING COUPLER EASTMAN KODAK COMPANY (US) 1997-06-24 US disclosed
EP-0763774-A1 Process for preparation of 2-equivalent 4-arylthio-5-pyrazolone magenta couplers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-19 EP disclosed
EP-0646840-B1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK CO (US) 1997-01-29 EP disclosed
US-5591569-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1997-01-07 US disclosed
US-5482821-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1996-01-09 US disclosed
US-5466568-A Multilayer light sensitive photographic film EASTMAN KODAK COMPANY (US) 1995-11-14 US disclosed
EP-0651289-A1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK COMPANY (US) 1995-05-03 EP disclosed
EP-0646841-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646840-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646842-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0232101-B1 Light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1994-03-23 EP disclosed
EP-0232101-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1987-08-12 EP disclosed
US-4587210-A COLORFASTNESS; DISCOLORATION INHIBITION; MAGENTA COUPLERS; WHITE BACKGROUND FUJI PHOTO FILM CO., LTD. (JP) 1986-05-06 US disclosed
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US disclosed
US-4293691-A Method for preparing magenta couplers having thioether groups FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed