Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634193 | 0.91 | KMT2A (0.38) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL11632128 | 0.88 | MEN1 (0.36) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL11817386 | 0.88 | MEN1 (0.41) | KMT2AALDH1A1MEN1NPSR1MAPK1 | |
| SCHEMBL11323104 | 0.86 | MAPT (0.41) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL8746973 | 0.86 | KMT2A (0.37) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL6161330 | 0.84 | NPC1 (0.43) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL7044353 | 0.84 | MEN1 (0.41) | RAB9AKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL11509676 | 0.83 | MEN1 (0.36) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL11837229 | 0.83 | KMT2A (0.37) | RAB9AKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL9340282 | 0.82 | RAB9A (0.44) | NPC1RAB9AKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711758-B1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1020450-B1 | 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound and process for preparation thereof | FUJI PHOTO FILM CO LTD (JP) | 2004-02-11 | — | — | EP | disclosed |
| EP-1020450-A1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5672714-A | HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0711758-A2 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-4106942-A | COMPOUNDS CONTAINING SULFIDE, KETONE, AND AMIDE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-15 | — | — | US | disclosed |