Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.71 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411245 | 0.89 | ACHE (0.76) | ACHEBCHE | |
| SCHEMBL9411572 | 0.88 | ACHE (0.77) | ACHEBCHE | |
| SCHEMBL8412833 | 0.85 | ACHE (0.60) | ACHEBCHEKDM4EPKM | |
| SCHEMBL7090686 | 0.83 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL9411550 | 0.82 | ACHE (0.66) | ACHEBCHE | |
| SCHEMBL6161760 | 0.81 | ACHE (0.73) | ACHEBCHE | |
| SCHEMBL6162285 | 0.79 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL6161716 | 0.79 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL6993296 | 0.79 | ACHE (0.75) | ACHEBCHE | |
| SCHEMBL4112194 | 0.76 | ACHE (0.45) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |