Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | AKT2 | P31751 | 2/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6165462 | 0.99 | BRD4 (0.53) | BRD4FPR2PIK3CDPIK3CAPIK3CB | |
| Hydrochloric Acid SCHEMBL6162622 | 0.90 | OPRD1 (0.52) | BRD4FPR2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL6161607 | 0.84 | SMYD3 (0.52) | BRD4FPR2AKT1SMYD3LMNA | |
| Hydrochloric Acid SCHEMBL6161918 | 0.83 | SMYD3 (0.51) | BRD4FPR2AKT1SMYD3LMNA | |
| SCHEMBL6163831 | 0.82 | CALCRL (0.47) | BRD4FPR2OPRD1LMNAOPRK1 | |
| SCHEMBL6163841 | 0.82 | CALCRL (0.47) | BRD4FPR2OPRD1LMNAOPRK1 | |
| Hydrochloric Acid SCHEMBL6163658 | 0.82 | CALCRL (0.47) | BRD4FPR2OPRD1LMNAOPRK1 | |
| Hydrochloric Acid SCHEMBL6163666 | 0.82 | CALCRL (0.47) | BRD4FPR2OPRD1LMNAOPRK1 | |
| Hydrochloric Acid SCHEMBL6161462 | 0.77 | CALCRL (0.46) | BRD4FPR2OPRD1LMNAOPRK1 | |
| SCHEMBL6162890 | 0.77 | MAPK1 (0.57) | BRD4FPR2OPRD1POLBOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |