Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039296 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL1038045 | 0.81 | LMNA (0.50) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL29413720 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL1680278 | 0.80 | ALDH1A1 (0.43) | PTGS2SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL23496291 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL3785560 | 0.79 | TDP1 (0.44) | SMN1; SMN2MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1134846 | 0.79 | F10 (0.48) | SLC6A4SLC6A3PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL18238945 | 0.79 | ABL1 (0.50) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL6161978 | 0.79 | IKBKB (0.41) | STAT3SLC6A4SLC6A3PTGS2PTGS1 | |
| SCHEMBL27514133 | 0.79 | MAPT (0.40) | SMN1; SMN2MAPTLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |