Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438933 | 0.84 | LMNA (0.51) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL1039296 | 0.84 | ALDH1A1 (0.50) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL1680278 | 0.82 | ALDH1A1 (0.43) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL23496291 | 0.82 | ALDH1A1 (0.48) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL29413720 | 0.82 | ALDH1A1 (0.48) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL7407881 | 0.81 | LMNA (0.49) | LMNAMCOLN3CA12CA2CA9 | |
| SCHEMBL6161641 | 0.81 | STAT3 (0.48) | LMNAMAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18238945 | 0.81 | ABL1 (0.50) | LMNAMAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3785560 | 0.81 | TDP1 (0.44) | MAPTSMN1; SMN2L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL1134846 | 0.81 | F10 (0.48) | LMNAMAPTSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444041-B | Method for synthesizing polysubstituted quinoline compound by photocatalysis | 安徽理工大学 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022068292-A1 | ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME | 陕西莱特光电材料股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| EP-1948616-B1 | 2-(BENZIMIDAZOL-1-YL)-ACETAMIDE BIARYL DERIVATIVES AND THEIR USE AS INHIBITORS OF THE TRPV1 RECEPTOR | ORGANON NV (NL) | 2011-01-26 | — | — | EP | disclosed |
| US-7482469-B2 | 2-(benzimidazol-1-yl)-acetamide bisaryl derivatives | N.V. ORGANON (NL) | 2009-01-27 | — | — | US | disclosed |
| EP-1948616-A1 | 2-(BENZIMIDAZOL-1-YL)-ACETAMIDE BIARYL DERIVATIVES AND THEIR USE AS INHIBITORS OF THE TRPV1 RECEPTOR | N.V. Organon (NL) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054480-A1 | 2-(BENZIMIDAZOL-1-YL)-ACETAMIDE BIARYL DERIVATIVES AND THEIR USE AS INHIBITORS OF THE TRPV1 RECEPTOR | N.V. ORGANON (NL) | 2007-05-18 | — | — | WO | disclosed |
| US-20070112034-A1 | 2-(benzimidazol-1-yl)-acetamide bisaryl derivatives | AKZO NOBEL N.V. (NL) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112034-A1 | 2-(benzimidazol-1-yl)-acetamide bisaryl derivatives | TRPV1, TRPV3, TRPV2 | LMNA 3518/4885MCOLN3 404/4885CA12 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.