Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.78 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.78 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128616 | 1.00 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL8442596 | 0.92 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL8379730 | 0.89 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL8442593 | 0.89 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL1032814 | 0.88 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL11823867 | 0.87 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL3990991 | 0.86 | TXNRD1 (0.75) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL5024763 | 0.85 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL8530183 | 0.85 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL10332736 | 0.84 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648510-B1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | IMMUNOGEN INC (US) | 2016-08-31 | — | — | EP | claimed |
| US-9242936-B2 | Methods for the preparation of charged crosslinkers | IMMUNOGEN, INC. (US) | 2016-01-26 | — | — | US | claimed |
| US-20150166482-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | IMMUNOGEN, INC. | 2015-06-18 | — | — | US | claimed |
| US-8598362-B2 | Methods for the preparation of charged crosslinkers | IMMUNOGEN, INC. (US) | 2013-12-03 | — | — | US | claimed |
| EP-2648510-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | ImmunoGen, Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| CN-103260406-A | Method for producing charged crosslinkers | IMMUNOGEN INC | 2013-08-21 | — | — | CN | claimed |
| US-20120165537-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | IMMUNOGEN, INC. (US) | 2012-06-28 | — | — | US | claimed |
| WO-2012078868-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | IMMUNOGEN, INC. (US) | 2012-06-14 | — | — | WO | claimed |
| JP-57032382-A | — | — | None | — | — | JP | disclosed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240166666-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR SA (ES) | 2024-05-23 | — | — | US | disclosed |
| US-20240131180-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2024-04-25 | — | — | US | disclosed |
| CN-117865987-A | Antitumor compounds | 法马马有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-0248932-B1 | PROCESS FOR PREPARING POLYAMIDES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-09 | — | — | EP | disclosed |
| US-4754016-A | Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0248932-A1 | Process for preparing polyamides | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-12-16 | — | — | EP | disclosed |
| US-4618721-A | Process for the preparation of nitrodiphenyl disulfides | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0116827-A2 | Process for the preparation of benzothiazoles | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |
| JP-S5732382-A | ANTICORROSIVE FOR AEROSOL CONTAINER | TOYO AEROSOL KOGYO KK | 1982-02-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166482-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | SCLY, STOM, STS | TXNRD1 2736/4885TXNRD3 1717/4885TXNRD2 2718/4885 |
| US-20240131180-A1 | DRUG ANTIBODY CONJUGATES | STT3B, STT3A, TTL | TXNRD1 1672/4885TXNRD3 2177/4885TXNRD2 3792/4885 |
| US-20240166666-A1 | ANTITUMORAL COMPOUNDS | TP53, TOP1, MCL1 | TXNRD1 543/4885TXNRD3 1210/4885TXNRD2 1060/4885 |
| US-20120165537-A1 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS | SCLY, STOM, STS | TXNRD1 2736/4885TXNRD3 1717/4885TXNRD2 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.