Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975526 | 0.85 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2POLBL3MBTL1MAPT | |
| SCHEMBL16975468 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL9228469 | 0.81 | ALDH1A1 (0.36) | ALDH1A1GFERSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL31716719 | 0.79 | GLS (0.38) | ALDH1A1GFERSMN1; SMN2L3MBTL1APOBEC3G | |
| SCHEMBL22119164 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL15171010 | 0.77 | POLB (0.47) | ALDH1A1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL27936843 | 0.76 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2POLBL3MBTL1MEN1 | |
| SCHEMBL22119352 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1GFERSMN1; SMN2POLBMAPT | |
| SCHEMBL22118830 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1GFERSMN1; SMN2POLBMEN1 | |
| SCHEMBL6154432 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2POLBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |