Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162033 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHRH3KMT2A | |
| SCHEMBL6162955 | 0.80 | MEN1 (0.59) | ALDH1A1L3MBTL1KDM4EHRH3KMT2A | |
| SCHEMBL6160208 | 0.79 | HRH3 (0.49) | ALDH1A1HRH3KMT2AMEN1DRD2 | |
| SCHEMBL6160199 | 0.79 | HRH3 (0.49) | ALDH1A1HRH3KMT2AMEN1DRD2 | |
| SCHEMBL6158891 | 0.78 | GAA (0.55) | KMT2ATSHRMEN1 | |
| SCHEMBL6158887 | 0.78 | GAA (0.55) | KMT2ATSHRMEN1 | |
| SCHEMBL6162831 | 0.74 | CCR3 (0.53) | KDM4EKMT2ATSHRMEN1DRD2 | |
| SCHEMBL6162841 | 0.74 | CCR3 (0.53) | KDM4EKMT2ATSHRMEN1DRD2 | |
| SCHEMBL1152082 | 0.73 | LMNA (0.58) | ALDH1A1L3MBTL1KDM4EKMT2ATSHR | |
| SCHEMBL1152080 | 0.73 | LMNA (0.58) | ALDH1A1L3MBTL1KDM4EKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |