Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.45 |
| ▸ | UGCG | Q16739 | 7/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162072 | 1.00 | GHSR (0.46) | GHSRPPARACCR1CYP3A4UGCG | |
| SCHEMBL6162268 | 0.87 | GHSR (0.59) | GHSRCCR1CYP3A4UGCGACE2 | |
| SCHEMBL6162272 | 0.87 | GHSR (0.59) | GHSRCCR1CYP3A4UGCGACE2 | |
| Hydrochloric Acid SCHEMBL6161348 | 0.86 | GHSR (0.58) | GHSRCCR1CYP3A4UGCGACE2 | |
| Hydrochloric Acid SCHEMBL6161349 | 0.86 | GHSR (0.58) | GHSRCCR1CYP3A4UGCGACE2 | |
| SCHEMBL6164689 | 0.84 | GHSR (0.48) | GHSRPPARACYP3A4UGCGCTSS | |
| SCHEMBL6164692 | 0.84 | GHSR (0.48) | GHSRPPARACYP3A4UGCGCTSS | |
| SCHEMBL6162874 | 0.82 | GHSR (0.48) | GHSRPPARACYP3A4UGCGCTSS | |
| SCHEMBL6162877 | 0.81 | GHSR (0.46) | GHSRPPARACYP3A4UGCGCTSS | |
| SCHEMBL6163155 | 0.81 | GHSR (0.46) | GHSRPPARACYP3A4UGCGCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |