SCHEMBL6162874

SCHEMBL6162874

CC(=O)C(N)C1(c2ccccc2)CCN(C(=O)C(COCc2ccccc2)NC(=O)C(C)(C)NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 4/20 0.48
PPARA Q07869 2/20 0.44
CTSS P25774 1/20 0.43
PPARG P37231 1/20 0.41
UGCG Q16739 2/20 0.41
CYP3A4 P08684 1/20 0.41
KLK7 P49862 2/20 0.39
KLK5 Q9Y337 2/20 0.39
TACR1 P25103 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6164689 0.88 GHSR (0.48) GHSRPPARACTSSPPARGUGCG
SCHEMBL6164692 0.88 GHSR (0.48) GHSRPPARACTSSPPARGUGCG
SCHEMBL6159933 0.88 GHSR (0.61) GHSRUGCGCYP3A4TACR1
SCHEMBL6162877 0.85 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6161360 0.83 GHSR (0.48) GHSRPPARACTSSPPARGUGCG
SCHEMBL6163155 0.83 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6164012 0.82 GHSR (0.45) GHSRPPARACTSSPPARGUGCG
SCHEMBL6164007 0.82 GHSR (0.45) GHSRPPARACTSSPPARGUGCG
SCHEMBL6162074 0.82 GHSR (0.46) GHSRPPARACTSSPPARGUGCG
SCHEMBL6162072 0.82 GHSR (0.46) GHSRPPARACTSSPPARGUGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP disclosed