Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 6/20 | 0.47 |
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162098 | 1.00 | HCRTR2 (0.47) | HCRTR2YAP1NR1H2ADORA1HCRTR1 | |
| SCHEMBL6162688 | 0.87 | NR1H2 (0.48) | HCRTR2NR1H2ADORA1HCRTR1KMT2A | |
| SCHEMBL6162692 | 0.87 | NR1H2 (0.48) | HCRTR2NR1H2ADORA1HCRTR1KMT2A | |
| SCHEMBL6164155 | 0.85 | P2RX7 (0.49) | HCRTR2BCL2P2RX7 | |
| SCHEMBL6165392 | 0.81 | PPARA (0.46) | NR1H2 | |
| SCHEMBL6165388 | 0.81 | PPARA (0.46) | NR1H2 | |
| SCHEMBL6163734 | 0.80 | TACR1 (0.48) | NR1H2KMT2AACE | |
| SCHEMBL6163736 | 0.80 | TACR1 (0.48) | NR1H2KMT2AACE | |
| SCHEMBL6160810 | 0.78 | PTPN1 (0.61) | YAP1ACEBCL2 | |
| SCHEMBL6160820 | 0.78 | PTPN1 (0.61) | YAP1ACEBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |