Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162692 | 1.00 | NR1H2 (0.48) | NR1H2GHSRPPARAHCRTR2CTSS | |
| SCHEMBL6165388 | 0.94 | PPARA (0.46) | NR1H2GHSRPPARACTSSPPARG | |
| SCHEMBL6165392 | 0.94 | PPARA (0.46) | NR1H2GHSRPPARACTSSPPARG | |
| SCHEMBL6162496 | 0.89 | PPARA (0.42) | GHSRPPARAHCRTR2CTSSHCRTR1 | |
| SCHEMBL6162501 | 0.89 | PPARA (0.42) | GHSRPPARAHCRTR2CTSSHCRTR1 | |
| SCHEMBL6163229 | 0.88 | DRD2 (0.44) | GHSRPPARAHCRTR2CTSSHCRTR1 | |
| SCHEMBL6163234 | 0.88 | DRD2 (0.44) | GHSRPPARAHCRTR2CTSSHCRTR1 | |
| SCHEMBL8413200 | 0.87 | PPARA (0.43) | GHSRPPARAHCRTR2CTSSHCRTR1 | |
| SCHEMBL6162098 | 0.87 | HCRTR2 (0.47) | NR1H2HCRTR2HCRTR1ADORA1KMT2A | |
| SCHEMBL6162093 | 0.87 | HCRTR2 (0.47) | NR1H2HCRTR2HCRTR1ADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |