Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28749082 | 0.93 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL2869784 | 0.90 | GLRA1 (0.62) | — | |
| Glycine SCHEMBL3384608 | 0.88 | — | — | |
| Glycine SCHEMBL2340760 | 0.88 | — | — | |
| Glycine SCHEMBL246859 | 0.88 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL474856 | 0.88 | — | — | |
| Glycine SCHEMBL28317820 | 0.88 | — | — | |
| Glycine SCHEMBL2299139 | 0.88 | — | — | |
| Glycine SCHEMBL391786 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.88 | GLRA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024114730-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER | 微境生物医药科技(上海)有限公司 | 2024-06-06 | — | — | WO | disclosed |
| WO-2024061172-A1 | PROLYL HYDROXYLASE INHIBITOR AND USE THEREOF | 苏中药业集团股份有限公司 | 2024-03-28 | — | — | WO | disclosed |
| CN-114230466-A | Dichloroacetic acid coupled diphenylethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-20210071036-A1 | POLISHING COMPOSITION | FUJIMI INCORPORATED (JP) | 2021-03-11 | — | — | US | disclosed |
| WO-2021033766-A1 | LITHOCHOLIC ACID DERIVATIVE HAVING VITAMIN D ACTIVITY | 国立大学法人お茶の水女子大学 | 2021-02-25 | — | — | WO | disclosed |
| US-10907073-B2 | Polishing composition | FUJIMI INCORPORATED | 2021-02-02 | — | — | US | disclosed |
| CN-105085429-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2019-12-10 | — | — | CN | disclosed |
| US-20190352536-A1 | POLISHING COMPOSITION | FUJIMI INCORPORATED (JP) | 2019-11-21 | — | — | US | disclosed |
| WO-2019189419-A1 | ANTI-CANCER AGENT-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2019-10-03 | — | — | WO | disclosed |
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |
| US-20150175541-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-25 | — | — | US | disclosed |
| EP-2881384-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-06-10 | — | — | EP | disclosed |
| US-20140117280-A1 | OXYGEN ABSORBER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-05-01 | — | — | US | disclosed |
| EP-2711077-A1 | OXYGEN ABSORBER | Mitsubishi Gas Chemical Company, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |
| EP-0308319-B1 | 4-PIPERIDINECARBOXAMIDE DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0308319-A2 | 4-Piperidinecarboxamide derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1989-03-22 | — | — | EP | disclosed |