SCHEMBL616279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13390055	0.97	RXFP1 (0.39)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL13718042	0.94	RXFP1 (0.40)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL12118432	0.92	HDAC1 (0.40)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL10189362	0.90	ALDH1A1 (0.38)	ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2
	SCHEMBL10189470	0.87	PDE4B (0.36)	ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2
	SCHEMBL619438	0.87	POLB (0.43)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL618300	0.86	MEN1 (0.47)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL3302975	0.86	RXFP1 (0.42)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	SCHEMBL3304211	0.84	TUBB4A (0.40)	RXFP1CYP3A4CYP2C19TUBB4ATUBB
	Hydrochloric Acid SCHEMBL615672	0.83	TUBB4A (0.40)	RXFP1CYP3A4CYP2C19TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.